BIOMAT Database Logo BIOMAT Database Logo

Interleukin-2 receptors on activated malignant and normal B-cells. 1984

T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene

UI MeSH Term Description Entries
D007106 Immune Sera Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTIGEN injection or infection with microorganisms containing the antigen. Antisera,Immune Serums,Sera, Immune,Serums, Immune
D007136 Immunoglobulins Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. Globulins, Immune,Immune Globulin,Immune Globulins,Immunoglobulin,Globulin, Immune
D007376 Interleukin-2 A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes. IL-2,Lymphocyte Mitogenic Factor,T-Cell Growth Factor,TCGF,IL2,Interleukin II,Interleukine 2,RU 49637,RU-49637,Ro-23-6019,Ro-236019,T-Cell Stimulating Factor,Thymocyte Stimulating Factor,Interleukin 2,Mitogenic Factor, Lymphocyte,RU49637,Ro 23 6019,Ro 236019,Ro236019,T Cell Growth Factor,T Cell Stimulating Factor
D008213 Lymphocyte Activation Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. Blast Transformation,Blastogenesis,Lymphoblast Transformation,Lymphocyte Stimulation,Lymphocyte Transformation,Transformation, Blast,Transformation, Lymphoblast,Transformation, Lymphocyte,Activation, Lymphocyte,Stimulation, Lymphocyte
D008223 Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. Germinoblastoma,Lymphoma, Malignant,Reticulolymphosarcoma,Sarcoma, Germinoblastic,Germinoblastic Sarcoma,Germinoblastic Sarcomas,Germinoblastomas,Lymphomas,Lymphomas, Malignant,Malignant Lymphoma,Malignant Lymphomas,Reticulolymphosarcomas,Sarcomas, Germinoblastic
D011971 Receptors, Immunologic Cell surface molecules on cells of the immune system that specifically bind surface molecules or messenger molecules and trigger changes in the behavior of cells. Although these receptors were first identified in the immune system, many have important functions elsewhere. Immunologic Receptors,Immunologic Receptor,Immunological Receptors,Receptor, Immunologic,Receptors, Immunological
D006377 T-Lymphocytes, Helper-Inducer Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions. Helper Cell,Helper Cells,Helper T Cell,Helper-Inducer T-Lymphocytes,Inducer Cell,Inducer Cells,T-Cells, Helper-Inducer,T-Lymphocytes, Helper,T-Lymphocytes, Inducer,Helper T-Cells,Cell, Helper T,Cells, Helper T,Helper Inducer T Lymphocytes,Helper T Cells,Helper T-Cell,Helper T-Lymphocyte,Helper T-Lymphocytes,Helper-Inducer T-Cell,Helper-Inducer T-Cells,Helper-Inducer T-Lymphocyte,Inducer T-Lymphocyte,Inducer T-Lymphocytes,T Cell, Helper,T Cells, Helper,T Cells, Helper Inducer,T Lymphocytes, Helper,T Lymphocytes, Helper Inducer,T Lymphocytes, Inducer,T-Cell, Helper,T-Cell, Helper-Inducer,T-Cells, Helper,T-Lymphocyte, Helper,T-Lymphocyte, Helper-Inducer,T-Lymphocyte, Inducer
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001402 B-Lymphocytes Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation. B-Cells, Lymphocyte,B-Lymphocyte,Bursa-Dependent Lymphocytes,B Cells, Lymphocyte,B Lymphocyte,B Lymphocytes,B-Cell, Lymphocyte,Bursa Dependent Lymphocytes,Bursa-Dependent Lymphocyte,Lymphocyte B-Cell,Lymphocyte B-Cells,Lymphocyte, Bursa-Dependent,Lymphocytes, Bursa-Dependent

Related Publications

T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
SLAMF receptors on normal and malignant B cells.
July 2019, Clinical immunology (Orlando, Fla.),
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Malignant B-cells have receptors for and respond to interleukin-2.
January 1986, Medical oncology and tumor pharmacotherapy,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.
October 1984, The Journal of experimental medicine,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Interleukin-2 effects on human B cells activated in vivo.
July 1987, Journal of clinical immunology,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes.
May 1986, Science (New York, N.Y.),
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Functional interleukin 2 receptors on B cells lacking Tac antigens.
September 1987, European journal of immunology,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
The malignant B cells from B-chronic lymphocytic leukemia patients release TAC-soluble interleukin-2 receptors.
August 1988, Blood,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells.
January 1984, Nature,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Transferrin receptors regulate proliferation of normal and malignant B cells.
January 1984, Current topics in microbiology and immunology,
T A Waldmann, and C K Goldman, and W J Leonard, and J M Depper, and R J Robb, and S J Korsmeyer, and W C Greene
Malignant chronic lymphocytic leukemia B cells express interleukin 2 receptors but fail to respond to interleukin 2's proliferative signal.
February 1987, Leukemia,
Copied contents to your clipboard!