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Chronic aortic regurgitation (AR) was induced by aortic valve perforation using catheterization techniques in 7 closed-chest puppies. Approximately 2 years after the creation of AR in these puppies, their growth was similar to that in littermate controls. A gradually progressive degree of left ventricular (LV) dilation and hypertrophy occurred as LV end-diastolic volume (average 116%) and mass (average 114%) increased in animals with AR compared with that in the littermate controls. The technique described to induce AR did not interfere with the normal growth and development of the animals, and permitted study of the functional characteristics of the resulting LV dilation and hypertrophy without added effects of thoracotomy and pericardiotomy.
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
January 1999,
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
May 1987,
The American journal of physiology,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
September 1993,
International journal of cardiac imaging,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
June 1983,
Journal of the American College of Cardiology,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
January 1997,
The Journal of thoracic and cardiovascular surgery,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
October 2005,
La Tunisie medicale,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
May 1985,
Clinical cardiology,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
November 1988,
Circulation,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
June 2015,
Journal of cardiovascular ultrasound,
R L Feldman, and
W W Nichols, and
L V Thompson, and
D M Paley, and
R Goldman, and
C R Conti, and
C J Pepine
July 1972,
Cardiovascular research,
