BIOMAT Database Logo BIOMAT Database Logo

Electric currents, bone remodeling, and orthodontic tooth movement. I. The effect of electric currents on periodontal cyclic nucleotides. 1980

Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff

Osteogenesis has been found to occur in response to the application of electric currents to bone. The objective of this experiment was to study the effects of D.C. electric currents on periodontal tissues in cats. Cyclic nucleotides, compounds known to be involved in cellular activation, were studied by immunohistochemistry in the involved tissues. Three groups of three young adult cats each were treated for 1, 3, and 7 days, respectively, by a device delivering 15 microamperes of direct current to bone osteoblasts and PDL cells stained intensely for cAMP and cGMP were observed adjacent to the cathode and anode, and bone apposition was found near the cathode. These results suggest that electric stimulation enhances cellular enzymatic phosphorylation activities in periodontal tissues and may be a potent tool in accelerating alveolar bone turnover.

UI MeSH Term Description Entries
D009712 Nucleotides, Cyclic Cyclic Nucleotide,Cyclic Nucleotides,Nucleotide, Cyclic
D010012 Osteogenesis The process of bone formation. Histogenesis of bone including ossification. Bone Formation,Ossification, Physiologic,Endochondral Ossification,Ossification,Ossification, Physiological,Osteoclastogenesis,Physiologic Ossification,Endochondral Ossifications,Ossification, Endochondral,Ossifications,Ossifications, Endochondral,Osteoclastogeneses,Physiological Ossification
D010513 Periodontal Ligament The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS). Alveolodental Ligament,Alveolodental Membrane,Gomphosis,Alveolodental Ligaments,Alveolodental Membranes,Gomphoses,Ligament, Alveolodental,Ligament, Periodontal,Membrane, Alveolodental,Periodontal Ligaments
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004560 Electricity The physical effects involving the presence of electric charges at rest and in motion.
D004599 Electric Stimulation Therapy Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the detection threshold of the skin to pain. Electrotherapy,Electrical Stimulation Therapy,Interferential Current Electrotherapy,Therapeutic Electric Stimulation,Therapeutic Electrical Stimulation,Therapy, Electric Stimulation,Electric Stimulation, Therapeutic,Electrical Stimulation, Therapeutic,Electrotherapy, Interferential Current,Stimulation Therapy, Electric,Stimulation Therapy, Electrical,Stimulation, Therapeutic Electric,Stimulation, Therapeutic Electrical,Therapy, Electrical Stimulation
D005260 Female Females
D006152 Cyclic GMP Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed) Guanosine Cyclic 3',5'-Monophosphate,Guanosine Cyclic 3,5 Monophosphate,Guanosine Cyclic Monophosphate,Guanosine Cyclic-3',5'-Monophosphate,3',5'-Monophosphate, Guanosine Cyclic,Cyclic 3',5'-Monophosphate, Guanosine,Cyclic Monophosphate, Guanosine,Cyclic-3',5'-Monophosphate, Guanosine,GMP, Cyclic,Guanosine Cyclic 3',5' Monophosphate,Monophosphate, Guanosine Cyclic
D000242 Cyclic AMP An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. Adenosine Cyclic 3',5'-Monophosphate,Adenosine Cyclic 3,5 Monophosphate,Adenosine Cyclic Monophosphate,Adenosine Cyclic-3',5'-Monophosphate,Cyclic AMP, (R)-Isomer,Cyclic AMP, Disodium Salt,Cyclic AMP, Monoammonium Salt,Cyclic AMP, Monopotassium Salt,Cyclic AMP, Monosodium Salt,Cyclic AMP, Sodium Salt,3',5'-Monophosphate, Adenosine Cyclic,AMP, Cyclic,Adenosine Cyclic 3',5' Monophosphate,Cyclic 3',5'-Monophosphate, Adenosine,Cyclic Monophosphate, Adenosine,Cyclic-3',5'-Monophosphate, Adenosine,Monophosphate, Adenosine Cyclic
D000539 Alveolar Process The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth. Alveolar Ridge,Alveolar Processes,Process, Alveolar,Processes, Alveolar,Ridge, Alveolar

Related Publications

Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement.
March 2014, The Angle orthodontist,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
[Effect of osthole on periodontal remodeling during orthodontic tooth movement in rats].
December 2019, Shanghai kou qiang yi xue = Shanghai journal of stomatology,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Effect of nicotine on orthodontic tooth movement and bone remodeling in rats.
July 2021, Korean journal of orthodontics,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement.
June 2022, Scientific reports,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
A periodontal ligament driven remodeling algorithm for orthodontic tooth movement.
May 2014, Journal of biomechanics,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Effect of constant currents on orthodontic tooth movement in the cat.
January 1975, Journal of dental research,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Mechanosensitive Piezo1 in Periodontal Ligament Cells Promotes Alveolar Bone Remodeling During Orthodontic Tooth Movement.
January 2021, Frontiers in physiology,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Nicotine effect on bone remodeling during orthodontic tooth movement: histological study in rats.
January 2014, Dental press journal of orthodontics,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
[Effect of low-energy microwave irradiation on orthodontic tooth movement and periodontal tissue remodeling in rats].
April 2022, Shanghai kou qiang yi xue = Shanghai journal of stomatology,
Z Davidovitch, and M D Finkelson, and S Steigman, and J L Shanfeld, and P C Montgomery, and E Korostoff
Periodontal ligament remodeling and alveolar bone resorption during orthodontic tooth movement in rats with diabetes.
January 2010, Diabetes technology & therapeutics,
Copied contents to your clipboard!