The Vogt-Koyanagi-Harada disease is an unusual affection, characterized by a meningeal syndrome, an ocular syndrome involving the anterior or posterior segment of the eye, and at last, manifestations of skin involvement such as poliosis, vitiligo and alopecia. Nowadays, the physiopathologic hypothesis, the most admitted, is the one of auto-immune process regarding the uveal pigment. Nosologically speaking, clinical epidemiologic and etiopathogenic arguments have allowed to join the Harada and Vogt-Koyanagi diseases under the same name: the Vogt-Koyanagi-Harada disease. The same arguments, except the epidemiologic ones, allow to make a similarity between this affection and uveo-meningitis on the hand, sympathetic ophthalmitis on the other hand. The use of oral corticosteröids and eventually immuno-suppressive agents constitute the only therapeutic methods, nowadays.