Biomaterial Database

Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid. 1980

C H Tadlock, and H V Aposhian

UI	MeSH Term	Description	Entries
D002614	Chelating Agents	Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.	Chelating Agent,Chelator,Complexons,Metal Antagonists,Chelators,Metal Chelating Agents,Agent, Chelating,Agents, Chelating,Agents, Metal Chelating,Antagonists, Metal,Chelating Agents, Metal
D004112	Dimercaprol	An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.	2,3-Dimercaptopropanol,2,3-Dithiopropan-1-o1,B.A.L.,BAL in Oil,British Anti-Lewisite,British Anti-Lewisite Agent,Cadmium 2,3-Dimercaptopropanol,Dicaptol,2,3 Dimercaptopropanol,2,3 Dithiopropan 1 o1,2,3-Dimercaptopropanol, Cadmium,Anti-Lewisite Agent, British,Anti-Lewisite, British,British Anti Lewisite,British Anti Lewisite Agent,Cadmium 2,3 Dimercaptopropanol,Oil, BAL in,in Oil, BAL
D004113	Succimer	A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.	DMSA,Dimercaptosuccinic Acid,2,3-Dimercaptosuccinic Acid,Butanedioic Acid, 2,3-Dimercapto-, (R,S)-Isomer,Chemet,Ro-1-7977,Succicaptal,Succimer Antimony Sodium Salt, (R,S)-Isomer,Succimer, (R,R)-(+,-)-Isomer,Succimer, Dipotassium Salt,Succimer, Disodium Salt,Succimer, Monosodium Salt,Succimer, Rhenium Salt,Succimer, Tin Salt,Tin Dimercaptosuccinate,meso-Dimercaptosuccinic Acid,2,3 Dimercaptosuccinic Acid,Acid, 2,3-Dimercaptosuccinic,Acid, Dimercaptosuccinic,Acid, meso-Dimercaptosuccinic,Dimercaptosuccinate, Tin,Dipotassium Salt Succimer,Disodium Salt Succimer,Monosodium Salt Succimer,Rhenium Salt Succimer,Ro 1 7977,Ro17977,Tin Salt Succimer,meso Dimercaptosuccinic Acid
D004195	Disease Models, Animal	Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	Animal Disease Model,Animal Disease Models,Disease Model, Animal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001151	Arsenic	A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)	Arsenic-75,Arsenic 75
D013438	Sulfhydryl Compounds	Compounds containing the -SH radical.	Mercaptan,Mercapto Compounds,Sulfhydryl Compound,Thiol,Thiols,Mercaptans,Compound, Sulfhydryl,Compounds, Mercapto,Compounds, Sulfhydryl
D014494	Unithiol	A chelating agent used as an antidote to heavy metal poisoning.	2,3-Dimercapto-1-propanesulfonic Acid,2,3-Dimercaptopropane 1-Sodium Sulfonate,2,3-Dimercaptopropane-1-sulfonate Sodium,2,3-Dimercaptopropanesulfonic Acid,DMPS,DMPS-Heyl,Dimaval,Mercuval,Sodium 2,3-Dimercaptopropane Sulfonate,Sodium 2,3-Dithiopropanesulfate,Unitiol,1-Sodium Sulfonate, 2,3-Dimercaptopropane,2,3 Dimercapto 1 propanesulfonic Acid,2,3 Dimercaptopropane 1 Sodium Sulfonate,2,3 Dimercaptopropane 1 sulfonate Sodium,2,3 Dimercaptopropanesulfonic Acid,2,3-Dimercaptopropane Sulfonate, Sodium,2,3-Dithiopropanesulfate, Sodium,DMPS Heyl
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D020261	Arsenic Poisoning	Disorders associated with acute or chronic exposure to compounds containing ARSENIC (ARSENICALS) which may be fatal. Acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as SEIZURES, mental status changes, and COMA. Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212)	Arsenic Encephalopathy,Arsenic Induced Polyneuropathy,Arsenic Poisoning, Inorganic,Arsenic Poisoning, Nervous System,Arsenic Poisoning, Organic,Encephalopathy, Arsenic,Inorganic Arsenic Poisoning,Nervous System Poisoning, Arsenic,Nervous System, Organic Arsenic Poisoning,Neurotoxicity Syndrome, Arsenical,Organic Arsenic Poisoning, Nervous System,Poisoning, Arsenic, Nervous System,Polyneuropathy, Arsenic-Induced,Arsenic Encephalopathies,Arsenic Poisonings,Arsenic Poisonings, Inorganic,Arsenic Poisonings, Organic,Arsenic-Induced Polyneuropathies,Arsenic-Induced Polyneuropathy,Arsenical Neurotoxicity Syndrome,Arsenical Neurotoxicity Syndromes,Encephalopathies, Arsenic,Inorganic Arsenic Poisonings,Neurotoxicity Syndromes, Arsenical,Organic Arsenic Poisoning,Organic Arsenic Poisonings,Poisoning, Arsenic,Poisoning, Inorganic Arsenic,Poisoning, Organic Arsenic,Poisonings, Arsenic,Poisonings, Inorganic Arsenic,Poisonings, Organic Arsenic,Polyneuropathy, Arsenic Induced,Syndrome, Arsenical Neurotoxicity,Syndromes, Arsenical Neurotoxicity