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A gel containing 0.5 mg prostaglandin E2 (PGE2) was extra-amniotically instilled 90 clinically normal gravidae at term, for ripening of the cervix before elective induction of labor by amniotomy and intravenous PGE2. An acceptable increase in the Bishop score was noted to have occurred in 87/90 women, when assessed eight hours after administration of the gel; 14 of these women were then in established labor, which progressed uneventfully. Four of the 90 subjects required cesarean section for cephalopelvic disproportion. No adverse maternal or fetal effects of the procedure were detected under careful clinical, electronic and biochemical monitoring. However, epidural anesthesia adversely influenced the acid-base equilibrium of the fetus.
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
October 1978,
Zeitschrift fur Geburtshilfe und Perinatologie,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
August 1978,
Zeitschrift fur Geburtshilfe und Perinatologie,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
April 1983,
Obstetrics and gynecology,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
March 1989,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
November 1977,
British medical journal,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
July 1986,
Obstetrics and gynecology,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
October 1985,
American journal of obstetrics and gynecology,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
August 2005,
Medical science monitor : international medical journal of experimental and clinical research,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
April 1977,
British journal of obstetrics and gynaecology,
M Thiery, and
P Defoort, and
G Benijts, and
R Derom, and
G Martens, and
J J Amy, and
H Van Kets, and
D De Schrijver
January 1987,
Annales chirurgiae et gynaecologiae. Supplementum,
