-transparent.png){kind=logo}
A study was made of muscle cAMP content in rabbits with dexamethasone-induced myopathy. The experiments were performed in 15 male rabbits weighing 2.5--3.5 kg. Steroidal myopathy was produced by daily administration of 0.8 dexamethasone/kg body weight. Muscle biopsy was taken on experimental days 1, 3, 7 and 14. The content of cAMP was determined by radioimmunoassay. The clinical signs of myopathy occurred by day 7. The animals were immobilized day 14. The content of cAMP increased after the first administration of dexamethasone and remained unchanged till the end of the experiment. The increased cAMP content may be accounted for by dexamethasone effect on the enzymatic system that monitors the processes of cAMP activation and inhibition.
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
January 2001,
Steroids,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
September 1985,
Zhonghua xin xue guan bing za zhi,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
June 1986,
Muscle & nerve,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
December 1971,
Annals of the New York Academy of Sciences,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
January 1985,
The EMBO journal,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
August 1972,
Acta physiologica Scandinavica,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
October 1982,
Experientia,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
January 1976,
Annals of the New York Academy of Sciences,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
October 1983,
Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases,
L O Badalian, and
V S Faustov, and
P A Temin, and
O I Gerasimova, and
L G Bykova
May 1984,
Arkhiv anatomii, gistologii i embriologii,
