-transparent.png){kind=logo}
Hereditary haemolytic anaemia with basophilic stippling caused by pyrimidine 5'-nucleotidase deficiency is described in three members of two unrelated Irish families. In one family, the disease was moderately severe and the patient's condition was improved by splenectomy. In the other family the haemolytic anaemia was well compensated. In neither family was there a marked elevation of reduced glutathione. The implications are that pyrimidine 5'-nucleotidase deficiency is a heterogeneous disorder, both clinically and biochemically. In more severe forms splenectomy may be beneficial.
Related Publications
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
January 1984,
International journal of tissue reactions,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
March 2000,
Bailliere's best practice & research. Clinical haematology,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
October 1977,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
August 1986,
British journal of haematology,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
June 1976,
Blood,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
February 1981,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
December 1978,
Metabolism: clinical and experimental,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
January 1989,
Acta haematologica,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
July 1979,
Clinica chimica acta; international journal of clinical chemistry,
J N McMahon, and
J E Lieberman, and
E C Gordon-Smith, and
E L Egan
January 1980,
Hemoglobin,
