Biomaterial Database

Effect of metronidazole on the intestinal microflora of the american cockroach, Periplaneta americana l. 1978

J W Bracke, and D L Cruden, and A J Markovetz

The effect of feeding to cockroaches the antimicrobial agent metronidazole, which acts specifically against anaerobes, was assessed by light and scanning electron microscopy, bacteriological examination, and methane formation. Types of organisms and total numbers were greatly reduced from controls. The health of mature adults was unaffected, but stunting occurred in subadult animals maintained on the antibiotic from hatching. The intracellular bacteria of the fat body were not affected by the drug. The results are discussed with respect to a proposed microbe-host extracellular symbiosis.

UI	MeSH Term	Description	Entries
D008795	Metronidazole	A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.	2-Methyl-5-nitroimidazole-1-ethanol,Bayer 5360,Clont,Danizol,Flagyl,Gineflavir,Metric,MetroGel,Metrodzhil,Metrogyl,Metronidazole Hydrochloride,Metronidazole Monohydrochloride,Metronidazole Phosphate,Metronidazole Phosphoester,Satric,Trichazol,Trichopol,Trivazol,Vagilen,2 Methyl 5 nitroimidazole 1 ethanol
D010526	Periplaneta	A genus in the family Blattidae containing several species, the most common being P. americana, the American cockroach.	Periplaneta americana,American Cockroach,American Cockroaches,American Cockroache,American Cockroachs,Cockroach, American,Cockroache, American,Cockroaches, American,Cockroachs, American,Periplaneta americanas,Periplanetas,americana, Periplaneta
D003058	Cockroaches	Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.	Blaberidae,Blattaria,Blattidae,Blattodea,Cryptocercidae,Dictyoptera,Polyphagidae,Cockroach,Blattarias,Blattodeas,Cockroache,Cockroachs,Dictyopteras
D003106	Colon	The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.	Appendix Epiploica,Taenia Coli,Omental Appendices,Omental Appendix,Appendices, Omental,Appendix, Omental
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia