Histochemistry of some steroid-dehydrogenases in epithelia of human seminal vesicle, deferential ampulla, and prostate gland. 1981

P Sirigu, and M Cossu, and R Scarpa, and A Pinna

The cytochemical localization of 17 beta-SDH, 3 beta-SDH, and 3 alpha-SDH was made in human seminal vesicle, deferential ampulla and prostate. The enzymes showed a remarkable activity in the epithelial cells of all glands. The epithelia of prostate, seminal vesicle, and deferential ampulla were able to metabolize androgens through the reductive pathway, characteristic of target tissues.

UI MeSH Term Description Entries
D008297 Male Males
D011467 Prostate A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM. Prostates
D004848 Epithelium The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body. Mesothelium,Epithelial Tissue,Mesothelial Tissue,Epithelial Tissues,Mesothelial Tissues,Tissue, Epithelial,Tissue, Mesothelial,Tissues, Epithelial,Tissues, Mesothelial
D005954 Glucosephosphate Dehydrogenase Glucose-6-Phosphate Dehydrogenase,Dehydrogenase, Glucose-6-Phosphate,Dehydrogenase, Glucosephosphate,Glucose 6 Phosphate Dehydrogenase
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012669 Seminal Vesicles A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Seminal Vesicle,Vesicle, Seminal,Vesicles, Seminal
D014649 Vas Deferens The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct. Ductus Deferens,Deferens, Ductus,Deferens, Vas
D015067 17-Hydroxysteroid Dehydrogenases A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-. 17 beta-Hydroxysteroid Dehydrogenases,Testosterone Dehydrogenases,17-Ketosteroid Reductases,17 Hydroxysteroid Dehydrogenases,17 Ketosteroid Reductases,17 beta Hydroxysteroid Dehydrogenases,Dehydrogenases, 17 beta-Hydroxysteroid,Dehydrogenases, 17-Hydroxysteroid,Dehydrogenases, Testosterone,Reductases, 17-Ketosteroid
D015096 3-Hydroxysteroid Dehydrogenases Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids. 3-beta-Hydroxysteroid Dehydrogenase,3 Hydroxysteroid Dehydrogenases,3 beta Hydroxysteroid Dehydrogenase,Dehydrogenase, 3-beta-Hydroxysteroid,Dehydrogenases, 3 Hydroxysteroid,Dehydrogenases, 3-Hydroxysteroid,Hydroxysteroid Dehydrogenases, 3
D045002 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH. 3 alpha-Hydroxysteroid Dehydrogenase,3 alpha-Hydroxysteroid Dehydrogenase (B-Specific),3 alpha-Hydroxysteroid Oxidoreductase,3alpha-Hydroxysteroid Dehydrogenase (B-specific),5 alpha-3 alpha-Hydroxysteroid Dehydrogenase,5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase,5-DP-3 alpha-HSO,NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase,3 alpha Hydroxysteroid Dehydrogenase,3 alpha Hydroxysteroid Oxidoreductase,5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase,Dehydrogenase, 3 alpha-Hydroxysteroid,NADPH 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase,Oxidoreductase, 3 alpha-Hydroxysteroid

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