BIOMAT Database Logo BIOMAT Database Logo

Interaction of imipramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ. 1981

M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi

UI MeSH Term Description Entries
D007099 Imipramine The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group. Imidobenzyle,Imizin,4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)-N,N-dimethyl-1-propanamine (1:2),Imipramine Hydrochloride,Imipramine Monohydrochloride,Imipramine Pamoate,Janimine,Melipramine,Norchlorimipramine,Pryleugan,Tofranil
D007473 Ion Channels Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS. Membrane Channels,Ion Channel,Ionic Channel,Ionic Channels,Membrane Channel,Channel, Ion,Channel, Ionic,Channel, Membrane,Channels, Ion,Channels, Ionic,Channels, Membrane
D009045 Motor Endplate The specialized postsynaptic region of a muscle cell. The motor endplate is immediately across the synaptic cleft from the presynaptic axon terminal. Among its anatomical specializations are junctional folds which harbor a high density of cholinergic receptors. Motor End-Plate,End-Plate, Motor,End-Plates, Motor,Endplate, Motor,Endplates, Motor,Motor End Plate,Motor End-Plates,Motor Endplates
D009469 Neuromuscular Junction The synapse between a neuron and a muscle. Myoneural Junction,Nerve-Muscle Preparation,Junction, Myoneural,Junction, Neuromuscular,Junctions, Myoneural,Junctions, Neuromuscular,Myoneural Junctions,Nerve Muscle Preparation,Nerve-Muscle Preparations,Neuromuscular Junctions,Preparation, Nerve-Muscle,Preparations, Nerve-Muscle
D011898 Ranidae The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica. Frogs, True,Rana,Frog, True,True Frog,True Frogs
D011950 Receptors, Cholinergic Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology. ACh Receptor,Acetylcholine Receptor,Acetylcholine Receptors,Cholinergic Receptor,Cholinergic Receptors,Cholinoceptive Sites,Cholinoceptor,Cholinoceptors,Receptors, Acetylcholine,ACh Receptors,Receptors, ACh,Receptor, ACh,Receptor, Acetylcholine,Receptor, Cholinergic,Sites, Cholinoceptive
D011978 Receptors, Nicotinic One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors. Nicotinic Acetylcholine Receptors,Nicotinic Receptors,Nicotinic Acetylcholine Receptor,Nicotinic Receptor,Acetylcholine Receptor, Nicotinic,Acetylcholine Receptors, Nicotinic,Receptor, Nicotinic,Receptor, Nicotinic Acetylcholine,Receptors, Nicotinic Acetylcholine
D004557 Electric Organ In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672) Electric Organs,Organ, Electric,Organs, Electric
D005399 Fishes A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D000109 Acetylcholine A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. 2-(Acetyloxy)-N,N,N-trimethylethanaminium,Acetilcolina Cusi,Acetylcholine Bromide,Acetylcholine Chloride,Acetylcholine Fluoride,Acetylcholine Hydroxide,Acetylcholine Iodide,Acetylcholine L-Tartrate,Acetylcholine Perchlorate,Acetylcholine Picrate,Acetylcholine Picrate (1:1),Acetylcholine Sulfate (1:1),Bromoacetylcholine,Chloroacetylcholine,Miochol,Acetylcholine L Tartrate,Bromide, Acetylcholine,Cusi, Acetilcolina,Fluoride, Acetylcholine,Hydroxide, Acetylcholine,Iodide, Acetylcholine,L-Tartrate, Acetylcholine,Perchlorate, Acetylcholine

Related Publications

M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Interaction of tricyclic antidepressants with the ionic channel of the acetylcholine receptor of Torpedo electric organ.
November 1981, Molecular pharmacology,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Thoughts on the channel size of the motor endplate acetylcholine receptor.
February 2002, British journal of anaesthesia,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Nereistoxin interaction with the acetylcholine receptor-ionic channel complex.
March 1980, Molecular pharmacology,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex.
April 1984, Fundamental and applied toxicology : official journal of the Society of Toxicology,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Cation selectivity of acetylcholine-activated ionic channel of frog endplate.
November 1979, The Journal of general physiology,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Interaction of analogs of histrionicotoxin with the acetylcholine receptor ionic channel complex and membrane excitability.
April 1984, The Journal of pharmacology and experimental therapeutics,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Interaction of merocyanine 540 with nicotinic acetylcholine receptor membranes from Discopyge tschudii electric organ.
March 1994, Biochimica et biophysica acta,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. I. Blockade of the ionic channel.
May 1984, Molecular pharmacology,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Regulation of motoneuron excitability via motor endplate acetylcholine receptor activation.
March 2005, The Journal of neuroscience : the official journal of the Society for Neuroscience,
M E Eldefrawi, and J E Warnick, and G G Schofield, and E X Albuquerque, and A T Eldefrawi
Compartmentalized transcription of acetylcholine receptor genes during motor endplate epigenesis.
May 1991, The New biologist,
Copied contents to your clipboard!