Biomaterial Database

[Aujeszky's disease: maternal immunity of piglets born of sows inoculated with various vaccines (author's transl)]. 1981

W T Truijen, and M J Tielen, and D H Brus, and A C van Exsel

Studies on the maternal state of immunity were done in 4-10 week-old piglets born of vaccinated sows free from Aujeszky's disease. The sows were inoculated with three different vaccines: two live vaccines (Aescovac Aujeszky) and the MK25 vaccine) and an inactivated vaccine (Geskyvac). The maternal state of immunity of the piglets was assessed from the titre of the virus-neutralizing (VN) antibodies in the blood. To do so, samples were taken from 300-400 4-10-week-old piglets per vaccine inoculated in the sow. At the same time, the VN titre of the blood of the sow was determined. The VN titres were highest in those sows which were vaccinated with Geskyvac. There was an obvious correlation between the VN titre of the sow and the maternal VN titres of the piglets. As a result, the maternal state of immunity in the sows vaccinated with Geskyvac also was highest. The value of the maternal VN titres in the assessment of maternal immunity was tested by exposing 28-37-day-old piglets showing various maternal VN titres to intracerebral challenge with 2000 TCID50 of Aujeszky disease virus (Van Doorn strain). Piglets showing VN titres higher than 1:8 were usually found to be immune against this challenge.

UI	MeSH Term	Description	Entries
D007112	Immunity, Maternally-Acquired	Resistance to a disease-causing agent induced by the introduction of maternal immunity into the fetus by transplacental transfer or into the neonate through colostrum and milk.	Fetal Immunity, Maternally-Acquired,Maternally-Acquired Immunity,Neonatal Immunity, Maternally-Acquired,Immunity, Maternally Acquired,Fetal Immunities, Maternally-Acquired,Fetal Immunity, Maternally Acquired,Immunity, Maternally-Acquired Fetal,Immunity, Maternally-Acquired Neonatal,Maternally Acquired Immunities,Maternally Acquired Immunity,Maternally-Acquired Fetal Immunities,Maternally-Acquired Fetal Immunity,Maternally-Acquired Immunities,Maternally-Acquired Neonatal Immunities,Maternally-Acquired Neonatal Immunity,Neonatal Immunities, Maternally-Acquired,Neonatal Immunity, Maternally Acquired
D011557	Pseudorabies	A highly contagious herpesvirus infection affecting the central nervous system of swine, cattle, dogs, cats, rats, and other animals.	Aujeszky's Disease,Aujeszky Disease,Aujeszkys Disease
D011558	Herpesvirus 1, Suid	A species of VARICELLOVIRUS producing a respiratory infection (PSEUDORABIES) in swine, its natural host. It also produces an usually fatal ENCEPHALOMYELITIS in cattle, sheep, dogs, cats, foxes, and mink.	Aujeszky's Disease Virus,Swine Herpesvirus 1,Aujeszky Disease Virus,Herpesvirus 1 (alpha), Suid,Herpesvirus Suis,Pseudorabies Virus,Suid Herpesvirus 1,Aujeszkys Disease Virus,Herpesvirus 1, Swine,Pseudorabies Viruses,Virus, Pseudorabies,Viruses, Pseudorabies
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000831	Animals, Newborn	Refers to animals in the period of time just after birth.	Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals
D000914	Antibodies, Viral	Immunoglobulins produced in response to VIRAL ANTIGENS.	Viral Antibodies
D013552	Swine	Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).	Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog
D014765	Viral Vaccines	Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.	Viral Vaccine,Vaccine, Viral,Vaccines, Viral