Biomaterial Database

[The progeny of women with treated congenital hypothyroidism (author's transl)]. 1981

A Rolland, and J L Chaussain, and P Borniche, and P Canlorbe, and J C Job

The progeny of 11 women with treated congenital hypothyroidism was studied. They had 17 pregnancies that led to 2 spontaneous abortions, 2 children dead in the first month after birth, and 13 living children. These 13 children have a normal psychomotor development. One of them has a lingual ectopic thyroid as her mother, one has a congenital cardiac defect, one has a minor anomaly of toes. The authors add a previously reported familial case of hypothyroidism in a mother and her four children.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011297	Prenatal Exposure Delayed Effects	The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.	Delayed Effects, Prenatal Exposure,Late Effects, Prenatal Exposure
D003409	Congenital Hypothyroidism	A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.	Cretinism,Myxedema, Congenital,Endemic Cretinism,Fetal Iodine Deficiency Disorder,Cretinism, Endemic,Hypothyroidism, Congenital
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man