-transparent.png){kind=logo}
We studied the effect of angiotensin II analogue (AII-A) and angiotensin I converting enzyme inhibitor (SQ 14,225) on blood pressure and the renin-angiotensin-aldosterone system in a patient with pseudo-Bartter's syndrome, who was a 26-year-old unmarried Japanese woman taking furosemide surreptitiously. The intravenous infusion of AII-A decreased blood pressure from 85/35 to 68/28 mmHg. This decrease in blood pressure was associated with an increment of plasma renin activity (PRA) and a decrement of plasma aldosterone concentration (PAC). Similarly, SQ 14,225 given orally decreased blood pressure to the same extent. An increment of PRA and a decrement of PAC were also observed. These results suggest that the renin-angiotensin system plays a considerable role in maintaining blood pressure in pseudo-Bartter's syndrome. Again, attention has to be paid to the possibility of surreptitious use of diuretics in an adult patient with persistent hypokalemic alkalosis, hyperactivity of the renin-angiotensin-aldosterone system and angiotensin II insensitivity simulating "true" Bartter's syndrome.
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
May 1979,
The New England journal of medicine,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
November 1978,
Nihon rinsho. Japanese journal of clinical medicine,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
December 1993,
American journal of kidney diseases : the official journal of the National Kidney Foundation,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
July 1996,
Hypertension (Dallas, Tex. : 1979),
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
July 1982,
The Journal of pharmacology and experimental therapeutics,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
August 1976,
Japanese circulation journal,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
January 1991,
European journal of clinical pharmacology,
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
May 1979,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
August 1974,
Lancet (London, England),
H Sasaki, and
T Kawasaki, and
M Fujisawa, and
Y Motooka, and
T Asano, and
M Okumura
February 2013,
Clinical research in cardiology : official journal of the German Cardiac Society,
