-transparent.png){kind=logo}
Pulmonary and systemic hemodynamics and arterial blood gases were measured in anesthetized and mechanically ventilated dogs before and after oral or intravenous administration of ethanol. Increases in mean pulmonary artery pressure and pulmonary vascular resistance occurred. Platelet antiserum-induced thrombocytopenia inhibition of prostaglandin synthesis with meclofenamate, or alpha-adrenergic blockade did not alter the pulmonary pressor response to ethanol. However, the increase in resistance following ethanol was abolished by hyperoxia and potentiated by hypoxia. Thus, it appears that the effect of ethanol is to augment hypoxic pulmonary vasoconstriction, whereas ethanol per se has no independent pulmonary pressor activity.
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
September 1981,
Anesthesiology,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
January 1986,
Nihon Kyobu Shikkan Gakkai zasshi,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
April 1991,
Journal of applied physiology (Bethesda, Md. : 1985),
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
March 1976,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
August 1990,
Anesthesiology,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
February 2001,
Critical care medicine,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
January 1987,
Masui. The Japanese journal of anesthesiology,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
October 1990,
The American review of respiratory disease,
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
August 2004,
Journal of applied physiology (Bethesda, Md. : 1985),
R C Doekel, and
E K Weir, and
R Looga, and
R F Grover, and
J T Reeves
January 1979,
Respiration; international review of thoracic diseases,
