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In a natural outbreak of sialodacryoadenitis virus it was observed that the incidence of clinical signs in spontaneous-hypertensive rats was 100%, and that these signs were of a severity not observed before in other strains of rats. Rats free of the virus were introduced so that the progress of the disease could be studied under natural conditions of spontaneous spread from the enzootically-affected breeding colony. The pathogenesis of the infection in these Sprague-Dawley rats has been recorded over a period of 10 days after their introduction to the colony, and the results of extensive serological screening have shown that the antibody response of the spontaneous-hypertensive rats to the virus is lower than in other strains of rat.
P Carthew, and
R P Slinger
January 1991,
Laboratory animal science,
P Carthew, and
R P Slinger
August 1977,
Nihon juigaku zasshi. The Japanese journal of veterinary science,
P Carthew, and
R P Slinger
December 1977,
Infection and immunity,
P Carthew, and
R P Slinger
October 1987,
Laboratory animal science,
P Carthew, and
R P Slinger
March 1990,
Laboratory animal science,
P Carthew, and
R P Slinger
April 1985,
Laboratory animal science,
P Carthew, and
R P Slinger
September 1987,
Veterinary pathology,
P Carthew, and
R P Slinger
June 1983,
Nihon juigaku zasshi. The Japanese journal of veterinary science,
P Carthew, and
R P Slinger
April 2001,
Physiology & behavior,
P Carthew, and
R P Slinger
October 1980,
Jikken dobutsu. Experimental animals,
