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This retrospective study over the decade 1969-1978 examines the precipitating factors and outcome in thirty-one patients with myasthenia gravis who developed ventilatory failure. An unusual example of chronic alveolar hypoventilation is discussed in detail. The most favourable outcome occurred in younger patients with a hyperplastic thymus, in contrast to a poorer outlook for older patients with an atrophic gland. Eleven patients died during the period of follow up: three deaths were unrelated to myasthenia but the remaining eight were attributed directly or indirectly to it. The mortality of 36% represents a marked improvement on a 70% mortality in a similar group of patients, reported from this hospital for the years 1960-1968.
I T Ferguson, and
R P Murphy, and
R G Lascelles
December 1998,
The Journal of laryngology and otology,
I T Ferguson, and
R P Murphy, and
R G Lascelles
November 1993,
Critical care medicine,
I T Ferguson, and
R P Murphy, and
R G Lascelles
July 1995,
The European respiratory journal,
I T Ferguson, and
R P Murphy, and
R G Lascelles
July 1996,
Intensive care medicine,
I T Ferguson, and
R P Murphy, and
R G Lascelles
May 1971,
Proceedings of the Royal Society of Medicine,
I T Ferguson, and
R P Murphy, and
R G Lascelles
April 1990,
British journal of urology,
I T Ferguson, and
R P Murphy, and
R G Lascelles
January 1984,
Cleveland Clinic quarterly,
I T Ferguson, and
R P Murphy, and
R G Lascelles
February 1991,
Chest,
I T Ferguson, and
R P Murphy, and
R G Lascelles
January 1993,
Khirurgiia,
I T Ferguson, and
R P Murphy, and
R G Lascelles
January 1986,
Cleveland Clinic quarterly,
