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A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocystis carinii, Cryptococcus neoformans, Candida albicans, herpes simplex virus, and cytomegalovirus. The immune deficiency was characterized as a persistent and profound selective decrease in the function as well as number of T lymphocytes of the helper/inducer subset and a possible activation of the suppressor/cytotoxic subset. Three patients died despite aggressive anti-infective therapy.
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
February 1984,
Southern medical journal,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
April 1982,
The New England journal of medicine,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
December 1981,
The New England journal of medicine,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
October 1982,
AJR. American journal of roentgenology,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
July 1994,
The Journal of infectious diseases,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
January 1983,
Sexually transmitted diseases,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
January 1983,
AIDS research,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
June 1983,
The Medical journal of Australia,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
June 1987,
Seminars in oncology,
D Mildvan, and
U Mathur, and
R W Enlow, and
P L Romain, and
R J Winchester, and
C Colp, and
H Singman, and
B R Adelsberg, and
I Spigland
January 1988,
NIDA research monograph,
