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Chronic experiments in dogs revealed that administration of neurotensin (3 and 10 mkg in 1.5 mkl) into the caudate nucleus altered the parameters of conditioned and unconditioned food reflexes: shortened the latency by 31% and augmented the reflexes by 56%. The microapplication of neurotensin in the same dosage into the posterior hypothalamus increased the stomach secretory function induced by histamine administration. The caudate nucleus and the hypothalamus seem to contain cells which have the receptors for neurotensin and take part in the mechanisms of conditioning and central influences on the digestive system's organs.
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