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Processing of the beta major and beta minor globin pre-mRNAs has been compared in murine erythroleukemia cells induced to synthesize hemoglobin by dimethyl sulfoxide or hemin treatment, using both the Northern blot technique and S1 nuclease mapping with 3' and 5' end-labeled probes. The small intervening sequence of both beta-globin pre-mRNAs was removed in one step, although minor amounts of incompletely spliced RNA were detected. During the processing of the large intervening sequence of beta major globin pre-mRNA two internal splice sites were clearly detected. On the contrary, the beta minor globin pre-mRNA did not show any internal splice sites. A model of processing of the mouse adult beta major globin pre-mRNA is proposed.
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
December 1983,
Archives of biochemistry and biophysics,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
October 1980,
The Journal of biological chemistry,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
January 1984,
Blood,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
January 1987,
Progress in clinical and biological research,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
July 1981,
Cell biology international reports,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
August 1977,
Proceedings of the National Academy of Sciences of the United States of America,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
February 1994,
Experimental hematology,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
March 1982,
Proceedings of the National Academy of Sciences of the United States of America,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
October 1989,
Molecular and cellular biochemistry,
D S Donaldson, and
A R McNab, and
G Rovera, and
P J Curtis
November 1977,
European journal of biochemistry,
