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Protein, hexose, amino sugar and sialic acid levels were determined in the perchlorosoluble fraction of serum from patients with myocardial infarct. Patients have significantly elevated mean values for all components. The hexose/perchlorosoluble protein and amino sugar/perchlorosoluble protein ratios were not significantly different when compared in normal and patient sera but the sialic acid/perchlorosoluble protein ratio was higher in patients with myocardial infarct. This change in sialic acid content could be related to an increased sialylation of glycoproteins normally present in serum. Particularly, an orosomucoid fraction with a higher content in sialic acid than that of the normal glycoprotein has been identified.
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Vutreshni bolesti,
