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Mice were inoculated with herpes simplex virus type 1 by the corneal route beforehand. Ten weeks after the inoculation, one group of mice was repeatedly treated with infectious virus-free, detergent-soluble extract of virus-infected cells (DSE) by the intraperitoneal route and the other group served as the controls. The virus recovery rate from the trigeminal ganglia of DES-treated mice was markedly reduced as compared with that of untreated mice, when a small amount of inocula was used. However, no significant decrease in the virus recovery rate was obtained when a large amount of inocula was used, suggesting that treatment with DSE had a limited effect on established ganglionic latency. The level of neutralizing antibody titers in the serum did not seem to be correlated with the efficacy of DSE in mice infected with a small amount of inocula.
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
July 1997,
Clinical microbiology reviews,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
May 1985,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
December 2003,
Expert reviews in molecular medicine,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
January 1989,
Lancet (London, England),
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
January 1984,
Clinics in dermatology,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
January 1977,
Duodecim; laaketieteellinen aikakauskirja,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
April 1979,
Antimicrobial agents and chemotherapy,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
September 1989,
Virology,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
January 1983,
Nippon Ganka Gakkai zasshi,
Y Ohashi, and
T Sugano, and
S Kato, and
K Sato
September 1975,
Ceskoslovenska oftalmologie,
