-transparent.png){kind=logo}
Thirty-seven patients with chronic cytopenia were studied using a CFU-c assay in agar. On the basis of the growth pattern three types of preleukaemic syndrome (PL) and two types of aplastic anaemia were distinguished. Further evaluation of the bone marrow dysfunction was attempted with a combined application of cytochemistry and electron microscopy for the morphologic study of cells proliferating in vitro. Well-defined maturation defects in the growing cells from the bone marrow of patients with PL were demonstrated with cytochemical stainings performed in agar. These results were supported by electron microscopic findings of Auer-body-like inclusions in "statu nascendi" in the vacuoles of preleukaemic cells. On the basis of our results a high risk group of PL for development of overt leukaemia and a group of patients with a grave prognosis in aplastic anaemia were distinguished. The data obtained are relevant for the clinical diagnosis and prognosis of patients with cytopenias.
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
January 1997,
Annals of hematology,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
July 1979,
Journal of clinical pathology,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
June 1978,
The Journal of clinical investigation,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
January 1975,
Hamatologie und Bluttransfusion,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
December 1989,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
January 1954,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
June 1976,
Haematologica,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
March 1993,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
June 1972,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
G Konwalinka, and
C Peschel, and
D Geissler, and
B Tomaschek, and
G Schuler, and
F Schmalzl, and
H Schaefer, and
H Huber, and
R Odavic, and
H Braunsteiner
January 2000,
Srpski arhiv za celokupno lekarstvo,
