Permeability of the blood-brain barrier in the rat after local proton irradiation. 1982

H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova

Rats were irradiated laterally through the brain with 200 MeV protons. The beam was of circular cross-section with a diameter of 5 or 7 mm. The doses were 50, 70, 100 and 150 Gy. After irradiation the rats were examined several times by use of injected 99Tcm-pertechnetate. The uptake of the substance increased to a maximum after 20 to 30 days and then decreased to a normal level. Differences in maximum uptake with respect to dose were significant only for the smaller beam diameter.

UI MeSH Term Description Entries
D009336 Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D010539 Permeability Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions. Permeabilities
D011522 Protons Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion. Hydrogen Ions,Hydrogen Ion,Ion, Hydrogen,Ions, Hydrogen,Proton
D011829 Radiation Dosage The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv). Sievert Units,Dosage, Radiation,Gray Units,Gy Radiation,Sv Radiation Dose Equivalent,Dosages, Radiation,Radiation Dosages,Units, Gray,Units, Sievert
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D001812 Blood-Brain Barrier Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue. Brain-Blood Barrier,Hemato-Encephalic Barrier,Barrier, Blood-Brain,Barrier, Brain-Blood,Barrier, Hemato-Encephalic,Barriers, Blood-Brain,Barriers, Brain-Blood,Barriers, Hemato-Encephalic,Blood Brain Barrier,Blood-Brain Barriers,Brain Blood Barrier,Brain-Blood Barriers,Hemato Encephalic Barrier,Hemato-Encephalic Barriers
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D005260 Female Females
D006470 Hemorrhage Bleeding or escape of blood from a vessel. Bleeding,Hemorrhages
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
December 1977, Brain research,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
June 1986, Biulleten' eksperimental'noi biologii i meditsiny,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
September 1979, Brain research,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
July 2002, Canadian journal of physiology and pharmacology,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
September 1979, Australian paediatric journal,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
February 1996, Experientia,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
May 1998, Journal of neuroimmunology,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
March 1975, Acta physiologica Scandinavica,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
January 1979, Transactions of the American Neurological Association,
H Lundqvist, and K Rosander, and M Lomanov, and V Lukjashin, and G Shimchuk, and V Zolotov, and E Minakova
April 2007, Neurologia (Barcelona, Spain),
Copied contents to your clipboard!