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Twelve of 13 diabetics with azotemic nephropathy experienced exacerbation of renal failure and decreased insulin requirement after coronary angiography utilizing radiographic contrast material. The single patient who did not develop acute renal failure had no evidence of decreased insulin requirement. Eleven of 12 patients had decreased insulin requirement: mean decrement in insulin dose, 40%; mean decrement in fasting blood glucose level, 33%; mean decrement in peak blood glucose level, 42%. The 12th patient underwent peritoneal dialysis against hypertonic glucose without need of an increased insulin dose. Eight of 11 patients experienced a total of 19 insulin reactions; one patient was hypoglycemic continuously, despite infusion of glucose and discontinuation of insulin. The decrement of insulin requirement was not proportional to the rise in either serum creatinine or potassium concentrations. We suggest that when acute renal failure occurs in diabetics, decreased insulin requirement should be anticipated and the insulin dose lowered.
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
May 1960,
Acta medica Scandinavica,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
April 1983,
Postgraduate medical journal,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
January 1982,
Clinical and experimental dialysis and apheresis,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
August 1980,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
December 1957,
Endocrinology,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
April 2007,
Diabetes research and clinical practice,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
March 1978,
Archives of internal medicine,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
January 1998,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
July 2005,
Kidney international,
L A Weinrauch, and
R W Healy, and
O S Leland, and
H H Goldstein, and
J A Libertino, and
F J Takacs, and
R F Bradley, and
R E Gleason, and
J A D'Elia
January 2006,
Clinical research in cardiology : official journal of the German Cardiac Society,
