-transparent.png){kind=logo}
The organization of the alpha-globin genes was studied by restriction endonuclease mapping, in subjects carrying the alpha variant Hb J Mexico. A subject homozygous for Hb J synthesized both Hb J (about 55%) and Hb A and had two alpha loci per chromosome. His restriction site map was found to be identical to that obtained with a normal DNA, except for a mutant Bgl II site which was observed on the Hb J chromosome proximal to the 5' alpha-locus. We have also mapped the DNA of a compound heterozygote for Hb J and alpha-thalassemia, who synthesizes 38% Hb J and we have found a single alpha gene corresponding to a - alpha 3.7 haplotype on one chromosome and two alpha genes, respectively alpha J and alpha A, on the other.
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
August 1977,
European journal of biochemistry,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
December 1980,
Blood,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
January 1976,
FEBS letters,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
June 1982,
British journal of haematology,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
February 1982,
Blood,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
June 1981,
American journal of clinical pathology,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
June 1980,
The Johns Hopkins medical journal,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
January 1988,
Hemoglobin,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
November 1998,
American journal of hematology,
G Trabuchet, and
F Morle, and
G Verdier, and
J Godet, and
M Benabadji, and
V M Nigon
November 1980,
British journal of haematology,
