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Cyclic adenosine 3', 5'-monophosphate (cyclic AMP) and adenyl cyclase and phosphodiesterase activities were determined in the specialized myocardial tissue of the conduction system of bovine heart and then compared with those in the ordinary myocardial tissue. The conduction system was comprised of the atrioventricular node (A-V node), the His bundle and the right and the left bundle branches (RBB and LBB). The content of cyclic AMP was higher in the ordinary myocardial tissue than in the specialized myocardial tissue. In the specialized myocardial tissue, its content was highest in the A-V node and lower in the His bundle than in the LBB and the difference between the contents in the RBB and the LBB was not significant. Adenyl cyclase activity as well as the content of cyclic AMP was higher in the ordinary myocardial tissue than in the specialized myocardial tissue. Its activity was higher in the A-V node than in the His bundle or the RBB, and the activities in the His bundle, the RBB and the LBB were similar. Phosphodiesterase activity was higher in the ordinary myocardial tissue than in the A-V node, and the activities in these 4 sections of the conduction system were similar.
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
January 1973,
Postepy higieny i medycyny doswiadczalnej,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
November 1977,
Pediatriia,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
May 1976,
Chemical & pharmaceutical bulletin,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
January 1977,
Journal of bacteriology,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
October 1984,
Thrombosis and haemostasis,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
October 1968,
Life sciences,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
January 1973,
The Journal of biological chemistry,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
December 1973,
Proceedings of the National Academy of Sciences of the United States of America,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
December 1979,
Neurochemical research,
Y Tamura, and
M Saito, and
K Matsumura, and
K Saito, and
T Kudo, and
K Ishimaru, and
T Niki, and
H Mori
May 1974,
Blood,
