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The rat thymocytes submitted to heating at 45 degrees C for 1 hr liberate plasma membrane fragments containing 5'-nucleotidase activity in the supernatant. The thymocytes were separated by ficoll density gradient centrifugation. High activity of 5'-nucleotidase per 10(6) cells was found in the supernatant of low density (1.069) subset of thymocytes. Thymocyte supernatant of rats treated with hydrocortisone demonstrated higher 5'-nucleotidase activity per 10(6) cells than in intact animals. This is due to an increase of the low density population of thymocytes in treated rats since the 5'-nucleotidase activity per 10(6) cells of the supernatant obtained from this density fraction is the same both in treated with hydrocortisone and intact rats. Hydrocortisone seems to induce a selection of the thymocytes with high 5'-nucleotidase activity.
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
February 1981,
Clinical immunology and immunopathology,
B V Oleĭnik, and
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February 1962,
Comptes rendus hebdomadaires des seances de l'Academie des sciences,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
September 1980,
FEBS letters,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
June 1952,
Science (New York, N.Y.),
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
July 1981,
The Histochemical journal,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
July 1959,
Journal of gerontology,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
January 1985,
Postepy higieny i medycyny doswiadczalnej,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
January 1983,
Leukemia research,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
February 1980,
Vrachebnoe delo,
B V Oleĭnik, and
A A Tarasova, and
I A Bezvershenko
January 1966,
Memorias do Instituto Butantan,
