-transparent.png){kind=logo}
Twelve healthy male volunteers received single daily oral doses of enalapril (EN) 10 mg for 8 consecutive days. Serum samples for prolactin (PRL) assay were taken on day 0 (baseline) at 12.00 h and 16.00 h, and on days 1 and 8 at 08.00 h (pre-drug), 12.00 h and 16.00 h. The 08.00 h values on day 1 served as the pre-drug baseline. There were no significant changes from baseline in serum PRL levels on days 1 and 8. All mean serum PRL levels on day 8 were significantly (P less than 0.01) lower than the upper limit of the normal range (2-15 ng/ml) found for healthy males in this laboratory. It is concluded that therapeutic doses of EN (10 mg/day, p.o.) for 8 consecutive days do not raise mean serum PRL levels above the normal range in healthy male volunteers.
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
November 1978,
British medical journal,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
November 1992,
The Journal of clinical psychiatry,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
November 1981,
Acta endocrinologica,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
January 1987,
Medicina,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
January 1986,
International journal of fertility,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
February 1989,
Journal of anatomy,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
December 1979,
The American journal of psychiatry,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
January 2001,
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
August 1975,
Research communications in chemical pathology and pharmacology,
W R McNabb, and
B A Brooks, and
F Noormohamed, and
A F Lant, and
H J Gomez, and
V J Cirillo, and
M Hichens, and
J A Bolognese
March 1976,
Archives of general psychiatry,
