[Pituitary gonadotropic function in uterine trophoblastic tumor]. 1983

M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova

A simultaneous determination of 3 gonadotropic hormones of the hypophysis (follitropin, lutronin and prolactin) using a radioimmunoassay in 33 patients with trophoblastic uterine tumors and 22 women on the 1st-8th day after normal delivery, has shown that there are not only significant differences in the nature of the secretion of hypophyseal gonadotropic hormones in pathology as compared to the normal postnatal period but also differences in different forms of trophoblastic tumors. These differences were characterized by a progressive, according to the severity of disease, independence between trophoblastic tissue function and gonadotropic function of the hypophysis. A marked suppression of follicle-stimulating function of the hypophysis after normal delivery decreased hydatidiform mole and trophoblastic tumors and was not observed in patients with chorioepithelioma of the uterus.

UI MeSH Term Description Entries
D007986 Luteinizing Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. ICSH (Interstitial Cell Stimulating Hormone),Interstitial Cell-Stimulating Hormone,LH (Luteinizing Hormone),Lutropin,Luteoziman,Luteozyman,Hormone, Interstitial Cell-Stimulating,Hormone, Luteinizing,Interstitial Cell Stimulating Hormone
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011388 Prolactin A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate. Lactogenic Hormone, Pituitary,Mammotropic Hormone, Pituitary,Mammotropin,PRL (Prolactin),Hormone, Pituitary Lactogenic,Hormone, Pituitary Mammotropic,Pituitary Lactogenic Hormone,Pituitary Mammotropic Hormone
D005260 Female Females
D005640 Follicle Stimulating Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity. FSH (Follicle Stimulating Hormone),Follicle-Stimulating Hormone,Follitropin
D006063 Chorionic Gonadotropin A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN). Chorionic Gonadotropin, Human,HCG (Human Chorionic Gonadotropin),Biogonadil,Choriogonadotropin,Choriogonin,Chorulon,Gonabion,Human Chorionic Gonadotropin,Pregnyl,Gonadotropin, Chorionic,Gonadotropin, Human Chorionic
D006065 Gonadotropins, Pituitary Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR) that stimulate gonadal functions in both males and females. They include FOLLICLE STIMULATING HORMONE that stimulates germ cell maturation (OOGENESIS; SPERMATOGENESIS), and LUTEINIZING HORMONE that stimulates the production of sex steroids (ESTROGENS; PROGESTERONE; ANDROGENS). Pituitary Gonadotropins
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
November 2021, Mayo Clinic proceedings,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
January 1985, Endokrynologia Polska,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
January 1954, Acta morphologica Academiae Scientiarum Hungaricae,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
April 1984, Akusherstvo i ginekologiia,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
February 1976, The Journal of clinical endocrinology and metabolism,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
June 1978, Akusherstvo i ginekologiia,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
November 1974, Polski tygodnik lekarski (Warsaw, Poland : 1960),
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
December 1980, Archives of disease in childhood,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
January 1976, Neuroscience and behavioral physiology,
M V Lomonosova, and A P Savinskaia, and A A Molodyk, and I A Gorshkova
January 1964, L'Annee endocrinologique,
Copied contents to your clipboard!