Biomaterial Database

A comparison of upper abdominal wound closure with monofilament nylon and polyglycolic acid. 1983

A R Askew

In a trial of 104 consecutive patients undergoing upper abdominal surgery, 62 wounds were closed with continuous layered nylon and 42 with interrupted mass PGA sutures. All wounds were closed by one surgeon. There was a significantly greater incidence of wound infection (P less than 0.01) and incisional hernia (P less than 0.05) in the group closed with PGA. Wounds closed with PGA took longer to suture (1.00 min/cm) than wounds closed with nylon (0.76 min/cm), a highly significant difference (P less than 0.001). From this study it is recommended that upper abdominal surgical wounds should be closed with a continuous nylon suture.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009757	Nylons	Polymers where the main polymer chain comprises recurring amide groups. These compounds are generally formed from combinations of diamines, diacids, and amino acids and yield fibers, sheeting, or extruded forms used in textiles, gels, filters, sutures, contact lenses, and other biomaterials.	Polyamides,Dermalon,Ethilon,Nylon,Polyamide,Supramid,Dermalons,Ethilons,Supramids
D011100	Polyglycolic Acid	A biocompatible polymer used as a surgical suture material.	Polyglycolide,Biofix,Dexon (Polyester),Dexon-S,Dexon S,DexonS
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D005260	Female		Females
D006555	Hernia, Ventral	A hernia caused by weakness of the anterior ABDOMINAL WALL due to midline defects, previous incisions, or increased intra-abdominal pressure. Ventral hernias include UMBILICAL HERNIA, incisional, epigastric, and spigelian hernias.	Ventral Hernia,Hernias, Ventral,Ventral Hernias
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man