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Synaptic transmission in parasympathetic ganglia of the cat urinary bladder was depressed by low doses (0.1-10 micrograms i.a.) of Leu- or Met-enkephalin but only by larger doses (10 micrograms-1 mg i.a.) of morphine. Naloxone blocked the depressant effects of the opiates as well as the depression produced by GABA, but did not block the depressant effects of norepinephrine. Intracellular recording revealed that Leu-enkephalin reduced EPSP-amplitude and lowered the probability of synaptically evoked firing without altering postsynaptic membrane potential or resistance. These findings suggest that enkephalinergic inhibition in bladder ganglia is mediated at least in part by a presynaptic site of action on delta opiate receptors.
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
June 1980,
Science (New York, N.Y.),
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
January 1994,
The Japanese journal of physiology,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
January 1981,
Doklady Akademii nauk SSSR,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
December 1983,
Biochemical and biophysical research communications,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
July 1981,
European journal of pharmacology,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
June 1971,
Nature: New biology,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
May 1978,
Brain research,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
January 2000,
Journal of neural transmission (Vienna, Austria : 1996),
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
October 1980,
Federation proceedings,
W F Simonds, and
A M Booth, and
K B Thor, and
N L Ostrowski, and
J R Nagel, and
W C de Groat
January 1953,
Acta physiologica Scandinavica. Supplementum,
