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In the present work a minibead method has been employed to study human hepatocyte receptors for albumin-coupled latex particles. The cell-latex reaction was observed in both phase contrast and scanning electron microscopy. It has been demonstrated that human hepatocytes exhibit bindings sites for different forms of glutaraldehyde-treated albumin, and the ligand has proved to be species-nonspecific. The albumin binding activity is temperature-dependent and can be only partially blocked by preincubation with free, glutaraldehyde-treated protein, unless hepatocytes are pretreated with vinblastine sulfate. The possible biological role of these receptors as regards the infection due to the hepatitis B virus (that shares common, but not identical binding sites) is also discussed.
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
June 2015,
Microscopy (Oxford, England),
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
February 1978,
Experientia,
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
August 2014,
Micron (Oxford, England : 1993),
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
September 1969,
Applied microbiology,
A Trevisan, and
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L Bianchi
December 1983,
Canadian journal of microbiology,
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
August 1998,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
April 1980,
Pediatrics,
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
June 2013,
Micron (Oxford, England : 1993),
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
July 1981,
Toxicological European research. Recherche europeenne en toxicologie,
A Trevisan, and
F Gudat, and
R Guggenheim, and
L Bianchi
March 1997,
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft,
