-transparent.png){kind=logo}
Human fibroblast cell lines established from skin biopsies of patients with Wiskott-Aldrich syndrome (WAS), a sex-linked immunodeficiency disorder, were found to have unusually high sensitivity to SV40 infection. When examined by immunofluorescence, two of the cell lines showed almost 100% positive staining for tumor and viral antigens 4 days after infection, while the third cell line showed 75% positive cells for both antigens. Marked cytopathic changes were seen in infected cultures and viral yields of 10(8) pfu/ml were obtained. After six serial passages in WAS cells, the viral DNA was examined by restriction endonuclease analysis and found to have HindIII cleavage pattern similar to that of DNA from SV40 grown in monkey cells.
T Miyamura, and
K Yoshiike, and
K K Takemoto
May 1998,
The Journal of pathology,
T Miyamura, and
K Yoshiike, and
K K Takemoto
May 1997,
Journal of immunology (Baltimore, Md. : 1950),
T Miyamura, and
K Yoshiike, and
K K Takemoto
July 2007,
Revista medica de Chile,
T Miyamura, and
K Yoshiike, and
K K Takemoto
November 1986,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
T Miyamura, and
K Yoshiike, and
K K Takemoto
December 2014,
Indian pediatrics,
T Miyamura, and
K Yoshiike, and
K K Takemoto
February 1989,
Thrombosis and haemostasis,
T Miyamura, and
K Yoshiike, and
K K Takemoto
October 2006,
The New England journal of medicine,
T Miyamura, and
K Yoshiike, and
K K Takemoto
September 1992,
The Journal of experimental medicine,
T Miyamura, and
K Yoshiike, and
K K Takemoto
May 2019,
British journal of haematology,
T Miyamura, and
K Yoshiike, and
K K Takemoto
August 2023,
British journal of haematology,
