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The cytoplasmic sialomucin in Paget cells of extramammary Paget's disease was examined by means of a battery of histochemical techniques. The staining methods used involved an electrolyte--Alcian Blue (pH 5.8), periodic acid--Schiff and azure A at selected pH levels. Methylation, saponification, borohydride reduction, acid hydrolysis, and digestion with diastase, neuraminidase (Vibrio cholerae) or chondroitinase ABC, were also employed. The cytoplasmic mucin was found to exhibit positive reaction for the above staining which were variously altered by the chemical modification procedures and diminished in intensity or abolished by digestion with neuraminidase. These results suggest that the cytoplasmic mucin is sialomucin without side-chain substituent in extramammary Paget's disease located in axillary or genital area, and with a substituent at C7 in the disease located in perianal area.
Y Sasai, and
T Nakama, and
M Kasada
January 1992,
Acta histochemica,
Y Sasai, and
T Nakama, and
M Kasada
January 1993,
Archives of dermatological research,
Y Sasai, and
T Nakama, and
M Kasada
July 1984,
The British journal of dermatology,
Y Sasai, and
T Nakama, and
M Kasada
August 2019,
Intractable & rare diseases research,
Y Sasai, and
T Nakama, and
M Kasada
April 1969,
The Tohoku journal of experimental medicine,
Y Sasai, and
T Nakama, and
M Kasada
January 1997,
The Kurume medical journal,
Y Sasai, and
T Nakama, and
M Kasada
October 1964,
Archivum histologicum Japonicum = Nihon soshikigaku kiroku,
Y Sasai, and
T Nakama, and
M Kasada
October 2011,
Dermatology online journal,
Y Sasai, and
T Nakama, and
M Kasada
April 2019,
Dermatology online journal,
