Role of splenectomy in prevention of hemorrhagic enteritis and death from hemorrhagic enteritis virus in turkeys. 1983

J E Ossa, and J Alexander, and G G Schurig

Hemorrhagic diarrhea, gross hemorrhagic enteritis, and death caused by intravenous virus injection of hemorrhagic enteritis virus (HEV) were prevented in otherwise susceptible turkey poults by surgical splenectomy. The splenectomized poults produced anti-HEV antibodies, which indicated that splenectomy did not completely prevent replication of the virus. These results indicate that the spleen is necessary for the development of the intestinal lesions of this disease. The role of a toxic factor in this disease is discussed.

UI MeSH Term Description Entries
D004752 Coronavirus, Turkey A species of CORONAVIRUS causing enteritis in turkeys and pullets. Bluecomb Virus,Enteritis Virus, Turkey,Transmissible Enteritis Virus of Turkeys,Transmissible Enteritis Virus, Turkeys,Turkey Coronavirus,Bluecomb Viruses,Coronaviruses, Turkey,Enteritis Viruses, Turkey,Turkey Coronaviruses,Turkey Enteritis Virus,Turkey Enteritis Viruses
D004753 Enteritis, Transmissible, of Turkeys An acute, highly contagious virus disease of turkeys characterized by chilling, anorexia, decreased water intake, diarrhea, dehydration and weight loss. The infectious agent is a CORONAVIRUS. Bluecomb of Turkeys,Transmissible Enteritis of Turkeys
D005779 Immunodiffusion Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction. Gel Diffusion Tests,Diffusion Test, Gel,Diffusion Tests, Gel,Gel Diffusion Test,Immunodiffusions,Test, Gel Diffusion,Tests, Gel Diffusion
D006471 Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000914 Antibodies, Viral Immunoglobulins produced in response to VIRAL ANTIGENS. Viral Antibodies
D013154 Spleen An encapsulated lymphatic organ through which venous blood filters.
D013156 Splenectomy Surgical procedure involving either partial or entire removal of the spleen. Splenectomies
D014422 Turkeys Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae. Meleagridinae,Meleagrididae

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