Biomaterial Database

Equilibrium dialysis of barbituric acids up to high concentrations of aqueous sodium alkylsulfonate solutions. 1984

C Treiner, and C Vaution, and F Puisieux

The partition coefficient K of four barbituric acids has been determined by the equilibrium dialysis method in aqueous solutions of sodium alkylsulfonate at 25 degrees C. The results obtained from dilute solutions to 0.3 M surfactant concentration are compared with solubility data for the same systems. The K values as deduced from Langmuir or Freundlich isotherms decrease with increasing surfactant concentration. The detergent used was an impure commercial product of known composition, which could be considered as a mixed surfactant. The change of partition coefficient with surfactant concentration as obtained from equilibrium dialysis experiments has been interpreted by assuming a continuous change of micelle composition.

UI	MeSH Term	Description	Entries
D008823	Micelles	Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.	Micelle
D003956	Dialysis	A process of selective diffusion through a membrane. It is usually used to separate low-molecular-weight solutes which diffuse through the membrane from the colloidal and high-molecular-weight solutes which do not. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Dialyses
D000476	Alkanesulfonates	Organic esters or salts of sulfonic acid derivatives containing an aliphatic hydrocarbon radical.	Alkyl Sulfonates,Sulfonates, Alkyl
D001463	Barbiturates	A class of chemicals derived from barbituric acid or thiobarbituric acid. Many of these are GABA MODULATORS used as HYPNOTICS AND SEDATIVES, as ANESTHETICS, or as ANTICONVULSANTS.
D012995	Solubility	The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Solubilities
D013501	Surface-Active Agents	Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.	Surface Active Agent,Surface-Active Agent,Surfactant,Surfactants,Tenside,Amphiphilic Agents,Surface Active Agents,Tensides,Active Agent, Surface,Active Agents, Surface,Agent, Surface Active,Agent, Surface-Active,Agents, Amphiphilic,Agents, Surface Active,Agents, Surface-Active