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Concentrations of cefotiam (CTM) in the exudate after abdominal operation were studied. The exudates were collected by 6 mm paper discs and the antibiotic concentrations were determined by the paper disc method using Proteus rettgeri ATCC 9250 as test organism. Comparison between agar well and paper disc assay for CTM in ascites specimens showed good correlation. Two grams of CTM was intravenously given to the patients after abdominal operations. The concentration of CTM in the exudate for 6 hours after injection was 0.4--14.2 micrograms/ml and this value exceeded the antibacterial level of CTM. It is, therefore, concluded that CTM will be effective for the postoperative prophylaxis.
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
January 1955,
Experientia,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
October 1993,
Kidney international,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
January 1949,
Helvetica physiologica et pharmacologica acta,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
October 1993,
Antimicrobial agents and chemotherapy,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
August 2010,
Analytical chemistry,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
June 1969,
Meditsinskaia radiologiia,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
January 1994,
Biological research,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
April 1968,
Biochimica et biophysica acta,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
January 2022,
Plant and soil,
H Nishindai, and
M Nakanishi, and
Y Kasai, and
I Hashimoto, and
Y Sawada, and
T Nakamura, and
T Fugono, and
K Maeda
April 1969,
The Analyst,
