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5-Hydroxytryptophan (5-HTP) elevated serum corticosterone concentrations when administered either intraperitoneally (i.p.) or intraventricularly. Inhibition of aromatic L-amino acid decarboxylase outside of the blood-brain barrier antagonized the corticosterone response, but only when the 5-HTP was given i.p. Stimulation of the pituitary-adrenocortical system by fenfluramine was not affected by 5,7-dihydroxytryptamine pretreatment, whereas the stimulation produced by quipazine administration was blocked by lesions of the basomedial hypothalamus. These results suggest that serotonergic drugs can act at multiple sites (i.e., both central and peripheral) to evoke a pituitary-adrenocortical response.
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
February 1981,
Neuroendocrinology,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
January 1978,
Neuroendocrinology,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
August 1997,
Pharmacology,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
January 1994,
Life sciences,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
January 1974,
Acta physiologica Academiae Scientiarum Hungaricae,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
March 1981,
Undersea biomedical research,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
January 1973,
Neuroendocrinology,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
February 1968,
Life sciences,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
June 1994,
Agents and actions,
J S Meyer, and
J F McElroy, and
R Yehuda, and
J Miller
April 1996,
The Journal of steroid biochemistry and molecular biology,
