Biomaterial Database

Effects of age, sex and stimulus parameters upon vestibulo-ocular responses to sinusoidal rotation. 1984

C Wall, and F O Black, and A E Hunt

We evaluated the vestibulo-ocular reflex (VOR) in 50 normal human subjects, uniformly distributed in age 20-59 years, and evenly distributed in sex by decade, using sinusoidal rotation over the frequency range of 0.005 to 1.0 Hz and three peak amplitudes of 25, 50, and 100 deg/sec. Age variations. The gain magnitude of the normal human VOR appears to decrease with increasing age. This trend becomes statistically significant at p less than 0.05 for the 0.005 and 0.01 Hz test points. Sex-related variations. There were no statistically significant differences in gain magnitude between the sexes but females had higher average gains than males for the lowest test frequencies. The phase data showed a trend with the average phase points for females being less than those for males. This difference was statistically significant at p less than 0.05 for the 0.005 Hz test frequency. Dynamic range. Increasing the stimulus amplitude by a factor of four yielded a small but statistically significant decrease in gain magnitude, thus suggesting a mild saturation-type of nonlinearity.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009760	Nystagmus, Physiologic	Involuntary rhythmical movements of the eyes in the normal person. These can be naturally occurring as in end-position (end-point, end-stage, or deviational) nystagmus or induced by the optokinetic drum (NYSTAGMUS, OPTOKINETIC), caloric test, or a rotating chair.	Nystagmus, Barany,Nystagmus, Caloric,Nystagmus, End-Position,Nystagmus, Positional,Nystagmus, Post-Rotatory,Nystagmus, Thermal,Nystagmus, Barany's,Nystagmus, Physiological,Physiologic Nystagmus,Barany Nystagmus,Barany's Nystagmus,Caloric Nystagmus,End-Position Nystagmus,Nystagmus, Baranys,Nystagmus, End Position,Nystagmus, Post Rotatory,Physiological Nystagmus,Positional Nystagmus,Post-Rotatory Nystagmus,Thermal Nystagmus
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D012018	Reflex	An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D004585	Electrooculography	Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.	EOG,Electrooculograms,Electrooculogram
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths