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Functional structural changes in the myocardium in different developmental phases of nephrotoxic glomerulonephritis were studied in rats. Electrocardiography, electron microscopy, and biochemical study of respiration, linked with oxidative phosphorylation, by polarography in the fraction of mitochondria isolated by differential centrifugation were employed. In experimental glomerulonephritis the ECG shifts were attended with diminished oxidative phosphorylation in the myocardial mitochondria, destructive changes in the cardiomyocytes (disorganization of mitochondria, myofibrils, endoplasmic reticulum), loosening and swelling of the basilar membranes, and changes and swelling in the capillaries and interstitium. The functional structural changes in the heart are reversible in character but persist for a longer period of time than the clinical manifestations of glomerulonephritis.
Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
May 2007,
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
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Z T Samoĭlova, and
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O E Kolesova, and
L V Khaliutina
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
February 1984,
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
January 1961,
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
June 1980,
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Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
August 2002,
Kidney international,
Z T Samoĭlova, and
G P Shul'tseva, and
N P Lebkova, and
O E Kolesova, and
L V Khaliutina
July 1983,
Wiener medizinische Wochenschrift (1946),
