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1 Following a seven day drug-free period, 80 depressed outpatients were randomly allocated to receive mianserin 60 mg nocte or nomifensine 150 mg daily. Blindness was maintained by the use of a double-dummy technique. 2 All measures of efficacy showed a trend in favour of mianserin throughout the four week trial, including the Hamilton Depression Scale (HDS), the Beck Self-rating Depression Inventory (BDI), the Clinical Global Impression (CGI) and the Efficacy Index. 3 Significant advantages in efficacy for mianserin were observed at day 14 on the HDS and at days 7, 14 and 21 on the CGI. 4 Substantially more patients experienced marked or moderate improvement during treatment with mianserin than with nomifensine. Side-effects were low with both drugs. 5 On the basis of the present trial and a previous comparison, mianserin appears to be a more effective antidepressant than nomifensine.
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
March 1980,
Pharmakopsychiatrie, Neuro-Psychopharmakologie,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
June 1979,
The American journal of psychiatry,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
January 1985,
Acta psychiatrica Scandinavica. Supplementum,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
January 1985,
Clinical therapeutics,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
January 1994,
International clinical psychopharmacology,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
April 1984,
The Journal of clinical psychiatry,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
July 1985,
Acta psychiatrica Scandinavica,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
May 1982,
Pharmacopsychiatria,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
January 1980,
International pharmacopsychiatry,
W Hamouz, and
R Van Dorth, and
R M Pinder, and
S M Stulemeijer
April 1984,
The Journal of clinical psychiatry,
