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Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia. 1983
S J Forman, and
W E Spruce, and
M J Farbstein, and
J L Wolf, and
E P Scott, and
A P Nademanee, and
J L Fahey, and
T Hecht, and
J A Zaia, and
R A Krance, and
D O Findley, and
K G Blume
Of 33 patients who had undergone allogeneic bone marrow transplantation during first complete remission of acute nonlymphocytic leukemia, 21 patients have now been followed in continued complete remission for 6-64 mo (median greater than 18 mo) without maintenance chemotherapy. The median age of the surviving patients is 27 yr. Transplant-related complications occurring throughout the first year after marrow grafting were fatal in 7 patients, and leukemic recurrence led to the death of 5 patients. The actuarial long-term disease-free survival is 60% and the actuarial remission rate is 79%.
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J A Zaia, and
R A Krance, and
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M J Farbstein, and
J L Wolf, and
E P Scott, and
A P Nademanee, and
J L Fahey, and
T Hecht, and
J A Zaia, and
R A Krance, and
D O Findley, and
K G Blume
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