-transparent.png){kind=logo}
Immune complexes have been purified from sera of patients with lepromatous leprosy, using solid phase conglutinin and analysed by SDS-PAGE. Some of their components have been immunologically identified after electrophoretic blotting on nitrocellulose. First, immunoglobulins, complement components (C1q, C1s, C3) and CRP were found in IC. Secondly, one mycobacterial antigen of 67 kD was directly identified in IC while two other components (20 kD and 14.4 kD) of possible M. leprae origin were also found in IC. This study suggests that lepromatous patients develop a good antibody response against some M. leprae antigens (33 kD and 12 kD), which are rapidly eliminated from circulation, while other M. leprae antigens (e.g. 67 kD) can persist in relative antigen excess, within circulating IC.
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
February 1983,
Clinical and experimental immunology,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
March 1993,
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
February 1997,
European journal of clinical investigation,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
June 2016,
Journal of clinical microbiology,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
January 1982,
Cancer immunology, immunotherapy : CII,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
March 1980,
Clinical and experimental immunology,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
March 1998,
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
December 1988,
Journal of clinical microbiology,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
January 1994,
Acta leprologica,
A K Chakrabarty, and
M Maire, and
K Saha, and
P H Lambert
January 1993,
Problemy tuberkuleza,
