[Genetic analysis of predator aggressiveness in mice]. 1983

E M Nikulina, and N K Popova

The character of inheritance of mouse predatory aggression towards crickets and locusts was investigated. The percentage of aggressive animals in the group and the latency of attack were indices of aggression. The hybridological analysis included obtaining reciprocal F1 and F2 hybrids and backcrosses of CBA and DD mice lines exhibiting polar parameters in predatory tests. Examination of hybrids and backcrosses showed that the high level of aggressiveness is dominant. Sex differences in aggression were seen neither in parent strains, nor in hybrids, reciprocal effects being also absent. The results of the hybridological analysis indicated that the predatory aggressions are under control of a small number of genes with a pronounced dominant effect. As a result of diallele analysis in three strains of mice, BALB/c, C57BL/6, DD and all combinations of first generation hybrids, it was found that almost all hybrids exhibited greater aggressiveness than that of parent strains or that it was similar to the indices of highly aggressive parents. Analysis of a strain combinative ability showed that the genotypic component is conditioned by a specific combinative ability, the influence of the total combinating ability and of the reciprocal effects being not significant. It was once more confirmed that the predatory aggression in mice is inherited as a high level dominancy of aggression and genes influencing its manifestation are localized in autosomes.

UI MeSH Term Description Entries
D008297 Male Males
D008815 Mice, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation. Inbred Mouse Strains,Inbred Strain of Mice,Inbred Strain of Mouse,Inbred Strains of Mice,Mouse, Inbred Strain,Inbred Mouse Strain,Mouse Inbred Strain,Mouse Inbred Strains,Mouse Strain, Inbred,Mouse Strains, Inbred,Strain, Inbred Mouse,Strains, Inbred Mouse
D011235 Predatory Behavior Instinctual behavior pattern in which food is obtained by killing and consuming other species. Predation,Behavior, Predatory,Predatory Behaviors
D003433 Crosses, Genetic Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species. Cross, Genetic,Genetic Cross,Genetic Crosses
D005260 Female Females
D005799 Genes, Dominant Genes that influence the PHENOTYPE both in the homozygous and the heterozygous state. Conditions, Dominant Genetic,Dominant Genetic Conditions,Genetic Conditions, Dominant,Condition, Dominant Genetic,Dominant Gene,Dominant Genes,Dominant Genetic Condition,Gene, Dominant,Genetic Condition, Dominant
D005816 Genetic Complementation Test A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell. Allelism Test,Cis Test,Cis-Trans Test,Complementation Test,Trans Test,Allelism Tests,Cis Tests,Cis Trans Test,Cis-Trans Tests,Complementation Test, Genetic,Complementation Tests,Complementation Tests, Genetic,Genetic Complementation Tests,Trans Tests
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000374 Aggression Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. Aggressions
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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