-transparent.png){kind=logo}
Concentrations of plasma renin substrate, serum oestradiol-17 beta, human chorionic gonadotrophin, sex-hormone binding globulin and plasma renin activity were measured in 77 samples from 74 patients with uterine bleeding during the first and second trimesters of pregnancy and in a control group of 29 normal pregnant women (51 samples). Mean concentrations of these substances were lower than control values in patients with an abnormal outcome of pregnancy. In patients with a normal outcome after uterine bleeding, concentrations were mostly within the control range. Serum oestradiol-17 beta concentration was superior to the other variables in predicting fetal outcome in the whole group. In patients with a live fetus at the time of blood sampling but who subsequently aborted, serum oestradiol-17 beta concentration was mostly normal, whereas plasma renin substrate was decreased. Our results suggest that plasma renin substrate may provide additional prognostic information to that given by serum oestradiol-17 beta measurement or ultrasonography in threatened abortion.
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
December 2005,
The Journal of steroid biochemistry and molecular biology,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
January 1985,
Acta obstetricia et gynecologica Scandinavica,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
January 2011,
Kathmandu University medical journal (KUMJ),
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
March 1959,
Clinical obstetrics and gynecology,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
August 1956,
The Journal of obstetrics and gynaecology of the British Empire,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
November 2018,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
June 1985,
British journal of obstetrics and gynaecology,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
January 1974,
Annales chirurgiae et gynaecologiae Fenniae,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
February 1981,
Journal of clinical pathology,
A S Siimes, and
I Immonen, and
U H Stenman, and
J E Kärkkäinen, and
F Pekonen, and
F Y Fyhrquist
January 2014,
Journal of the Turkish German Gynecological Association,
