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Amino acids and proteins were found to produce different effect on the synthesis of bacitracin and exoprotease by Bacillus licheniformis 28 KA depending on the age of the cells. The enzyme synthesis was induced by amino acids and proteins only in the cells at the exponential growth phase. No correlation could be established between the antibiotic and proteolytic activities. The optimal protease synthesis was found in a medium with isoleucine whereas the antibiotic synthesis was optimal in a medium containing no amino acids.
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