-transparent.png){kind=logo}
Women with breast carcinoma and four or more involved ipsilateral axillary lymph nodes were randomly assigned to receive an induction course and 2 yr of maintenance chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil (CMF, 150 patients), CMF plus vincristine and prednisone (CMFVP, 166 patients), or chemoimmunotherapy with CMF plus the methanol extraction residue of BCG (CMF-MER, 85 patients). After 5 yr of accrual and a median follow-up of 34 mo, CMFVP is superior to CMF (p less than 0.01) with disease-free survival estimates at 4 yr of 60% for CMFVP compared to 45% for CMF. The disease-free survival advantage of CMFVP over CMF was greater in postmenopausal (p = 0.02) than in premenopausal patients (p = 0.09). CMF-MER was similar to CMF alone. CMF related side effects were similar in each regimen (see text), except for a greater incidence of leukopenia during induction with CMF than with CMFVP (p less than 0.01).
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
September 2005,
The journals of gerontology. Series A, Biological sciences and medical sciences,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
September 2013,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
July 2009,
Cancer,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
December 1977,
Archives of internal medicine,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
January 1978,
Antibiotics and chemotherapy,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
January 1992,
Breast cancer research and treatment,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
September 2001,
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
January 1996,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
April 2007,
The Cochrane database of systematic reviews,
D C Tormey, and
V E Weinberg, and
J F Holland, and
R B Weiss, and
O J Glidewell, and
M Perloff, and
G Falkson, and
H C Falkson, and
P H Henry, and
L A Leone
October 1985,
World journal of surgery,
