-transparent.png){kind=logo}
The sequence of the appearance of fibronectin in the rabbit cornea after thermal burn was investigated by indirect immunofluorescent microscopy. One day after thermal burn, the keratocytes disappeared completely from the burned area, and faint fibronectin-specific fluorescence was detected beneath the epithelium and on the stromal side of the Descemet's membrane. On day 3, activated keratocytes began to migrate to the burned lesion. Fibronectin was detected in the burned area as well as in the surrounding uninjured area, and on both sides of the Descemet's membrane. One week after the burn, the keratocytes had increased in the lesion and, concomitantly, fibronectin-specific fluorescence could be observed at the locations corresponding to the keratocytes. Fibronectin in the surrounding area gradually diminished. After 4 weeks, activated keratocytes had accumulated in the lesion, and fibronectin was detected only in the central lesion and at the level of the Descemet's membrane. Thus the appearance of fibronectin was concordant with the appearance of the keratocytes, and this suggests that fibronectin may be involved in the wound-healing of thermally burned rabbit corneas.
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
March 1993,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
March 1984,
Current eye research,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
February 1986,
Nippon Ganka Gakkai zasshi,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
January 1985,
Cornea,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
September 1994,
Yan ke xue bao = Eye science,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
May 1985,
Journal of cellular physiology,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
January 1992,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
June 1997,
Yan ke xue bao = Eye science,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
January 1969,
Voprosy meditsinskoi khimii,
Y Ohashi, and
S Nakagawa, and
T Nishida, and
T Suda, and
K Watanabe, and
R Manabe
January 1996,
Voprosy meditsinskoi khimii,
