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The influence of several prognostic factors in kidney transplantation was studied by the actuarial method from the data collected on 332 grafts performed at one center from 1971 to 1982. Taking into account the various interactions between these factors, 3 survival parameters were calculated: patient's survival, immunologic tolerance of the graft and overall graft survival. The relevant prognostic factors, ranked in decreasing order, are: origin of the graft, immunosuppressive therapy, recipient's age, recipient's HBs status and number of blood transfusions administered prior to transplantation, HLA presensitization and HLA-A,B matching. Integration of these factors leads to a precise estimation of the risk of transplantation from the characteristics of the graft and those of the potential recipients, thereby allowing to select the best candidate.
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